The PSA test can detect high levels of PSA that may indicate the presence of prostate cancer. However, many other conditions, such as an enlarged or inflamed prostate, also can increase PSA levels. Therefore, determining what a high PSA score means can be complicated. Diagnosis of prostate cancer (PC) has posed a challenge worldwide due to the sophisticated and costly diagnostics tools, which include DRE, TRUS, GSU, PET/CT scan, MRI, and biopsy. These diagnostic techniques are very helpful in the detection of PCs; however, all the techniques have their serious limitations. Biosensors are easier to fabricate and do not require any cutting-edge technology as Second, as we showed in another analysis of the PCPT, finasteride improves the sensitivity of the PSA test for the detection of overall and high-grade prostate cancer. Because the decision to perform prostate biopsies during the study was based on PSA levels, this may have contributed to increased detection of prostate cancer, in general, and 2 The Prostate Health Index: Filling the Diagnostic Gap Results of the multi-center pivotal clinical trial showed that Beckman Coulter phi values significantly enhanced the clinical specificity for prostate cancer detection in men with PSA in the the 4 to 10 ng/mL PSA range.3 A Beckman Coulter phi value of 27.0 corresponds to 90% clinical sensitivity The Select mdx test measures the amount of two genes associated with aggressive prostate cancer. The measurement of these prostate cancer specific genes in combination with traditional clinical risk factors—such as your age, PSA (prostate-specific antigen) level, prostate volume, family history of prostate cancer, and the outcome of a digital rectal examination (DRE) results in your Select The first-round prostate cancer IRRs for PSA were notably high due to the strong correlation between a diagnosis and the screening test leading to the diagnosis. Discussion. similar test specificity was found for DRE and free/total PSA (0.91 vs. 0.85). The test sensitivity, however, was lower for DRE (0.15 compared with 0.32 for free/total qNOIa.

sensitivity of psa test for prostate cancer